direct lineage reprogramming

A new finding by Harvard stem cell biologists demonstrates that it is possible to turn one type of already differentiated neuron into another within the brain.

The discovery by Paola Arlotta and Caroline Rouaux “tells you that maybe the brain is not as immutable as we always thought, because at least during an early window of time one can reprogram the identity of one neuronal class into another,” said Arlotta, an Associate Professor in Harvard’s Department of Stem Cell and Regenerative Biology (SCRB).

 Arlotta and Rouaux now have proven that neurons too can change their mind. Arlotta targeted callosal projection neurons, which connect the two hemispheres of the brain, and turned them into neurons similar to corticospinal motor neurons, one of two populations of neurons destroyed in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease.

The work in Arlotta’s lab is focused on the cerebral cortex. These experiments will facilitate work in a new field of neurobiology that explores the boundaries and power of neuronal reprogramming.

Link to the story on neorosciencenews.com

Harvard University Department of Molecular and Cellular Biology

amazing google facts

 

Infographic from makeuseof.com

620,000,000 daily visitors to Google! Processes around 20 petabytes of information on a daily basis. In the past 5 years, it has indexed over 50 billion web pages.

your biggest fan

Do you have a biggest fan? How we see ourselves is how others will see us. With this in mind, let's proceed to the next level.

Do you have enemies? Think this. Maybe there is no such thing as enemies.  No one's vying for our demise, so much as their own ascension. Maybe having opposition is our desperate explanation for why we face conflict we don't understand. Maybe our self-consciousness is behind why we feel judged by others.

Maybe becoming our own biggest fan will destroy whatever we perceived was against us.

Maybe becoming our biggest fan is the answer. Have confidence and conviction. This will attract a support system. There are no fair-weather fans by becoming your biggest fan. We must first support ourselves. We are our own complete and total support system

This notion leads to a better feeling within ourselves. We will have no enemies. We will have no opposition. We will have no conflict.

This attitude comes with practice. Be grateful for what you have and for what you are about to receive. Keep your thoughts positive. Go for the big picture. Make yourself part of the big picture. The sum is greater than all of its parts. A part is greater than the whole. We are that part.

inside out

We all become the media when we post. It's not about us. It's about the social media platform. It's about leveraging the medium. We build relationships and networks. We share.

Becoming a social entity transforms the organization from the inside out. Becoming social  starts from the inside.

So must we start from the inside? Must we find ourselves from the inside out? Finding our "within" so we are better in tune with the culture and society allows us to better understand our purpose and intent.

When studying social media I have been amazed at the results. One item that comes to mind is the amount of users on social media. This is really astounding. We are part of this astonishment! Our journey is directed by the inside out.

We have to invest in ourselves. Invest for the long haul, and we'll achieve more. This is how to create value. Concentrate on the inner thoughts that will be successful. Focus on the knowledge needed for solid concentration that puts the pieces of the puzzle together.

Measurement in social media is the lasting friendships and understanding garnered from friends and followers. Be prepared to enjoy yourself.

“Becoming a social business transforms the organization from the inside out, connecting the internal with the external in a way that enhances relationships and creates shared value for the people, the business and ecosystem as a whole.” - See more at: http://themarketingnutz.com/2013/08/difference-between-social-media-social-business-can-your-business-touch-its-toes/#sthash.jIfVbfKV.dpuf

“Becoming a social business transforms the organization from the inside out, connecting the internal with the external in a way that enhances relationships and creates shared value for the people, the business and ecosystem as a whole.” - See more at: http://themarketingnutz.com/2013/08/difference-between-social-media-social-business-can-your-business-touch-its-toes/#sthash.jIfVbfKV.dpuf

“Becoming a social business transforms the organization from the inside out, connecting the internal with the external in a way that enhances relationships and creates shared value for the people, the business and ecosystem as a whole.” - See more at: http://themarketingnutz.com/2013/08/difference-between-social-media-social-business-can-your-business-touch-its-toes/#sthash.jIfVbfKV.dpuf

concentration

Concentration means an uneven, unbroken flow of thought. All knowledge is the result of concentration. Thus the mind becomes a magnet and the desire to know draws the knowledge and makes it ours. Concentration requires the control of the physical, mental, and spiritual being. The subconscious mind may be aroused and brought into action to serve us for any purpose by concentration. The result of continuous concentration results in a patient, persistent, persevering, well-regulated system. Concentration unfastens the prison bars of unbelief, weakness, impotence, and self-belittlement. This allows us to enter into a realization of the joy of overcoming.

Desire is largely subconscious. Subconsciousness arouses the latent faculties of the mind and brings the object of conscious desire within reach. Spiritual Truth is the controlling factor to translate modes of thought into character and consciousness. Desire is the strongest mode of action.

All mental discovery and attainment are the result of desire plus concentration. Desire added to concentration will wrest any secret from Nature. Concentration is the transmutation of thoughts into practical values. It leads to intuitive perceptions and immediate insight and is equivalent to being a great actor forgetting oneself in the portrayal of his character, swaying the audience by the realism of the performance.

In experiencing great emotions that go with great thoughts, the mind is in a state where it appreciates the value of higher things. The spirit of initiative and originality is born. The value of concentration encourages decision of character. The mind becomes efficient and desire is the predominating force. The mind is an engine whose power is undreamed. Thought is an omnipotent power, the ruler and creator of all form and all events occurring in form. Thought enables man to harness all other natural power.

Vibration is the action of thought. There is nothing mysterious concerning the power of thought. If we concentrate on some matter of importance, the intuitive power will set in operation. The mind absorbs the object of its attention. The mind gives it life and being. Help will come in the nature of information which will lead to success.

Strength is determined by mental attitude. Keeping the thought in mind, it will gradually take tangible form. Turn thought within to take hold of the basic principles, the heart, and the spirit of things. When we get to the heart of things, it is comparatively easy to understand and command them. Let thought dwell upon the object.

"Thought is the property of those only who can entertain it." - Emerson

the regius poem

When thou meetest a worthy man,
Cap and hood thou hold not on;
In church, in market, or in the gate,
Do him reverance after his state.
If thou goest with a worthier man
Then thyself thou art one,
Let thy foremost shoulder follow his back,
For that is nurture without lack;

A portion of the Regius Poem, circa 1390. First published in the U.S. in 1840.

It is far more ancient than that of the other manuscripts, showing that it was written in an earlier stage of the English tongue. It belongs to Early English which succeeded the Anglo-Saxon.

refine

Increasing the volume doesn't improve our message. Higher volume doesn't increase the message's resonance with our audience.

This is where visual communication comes in handy. Showing something cuts through potential confusion.

the decision doctrine

One of the most powerful qualities of doctrine is its scalability. Doctrine can be nested inside other doctrine. For example, the doctrine related to helicopters is nested inside the network-centric approach to fighting war.

There are four tenets:

• A robustly networked force improves information sharing;
• Information sharing enhances the quality of information and shared situational awareness;
• Shared situational awareness enables collaboration and self-synchronization, and enhances sustainability and speed of command; and
• These, in turn, dramatically increase mission effectiveness.

The distributed approach to managing helicopters flowed from this higher level doctrine, especially in how to achieve self-synchronization. A shared framework was used so all helicopters could operate. Action was taken to use the framework. Doctrine was used to improve performance.

Let's look at the event. What guidelines are needed to produce a successful event?

• Rules: the power of ideas to change attitudes.
• Responsibilities: who is the event for? Define this guide decisions.
• Resources: best practices for designing, promoting and sponsoring.

Good doctrine becomes embedded in the culture.

How can you apply doctrine?

• See where you might already have elements of doctrine.
• Identify areas.
• Involve the broader team
• Focus on principles, not policies.

Good doctrine provides the empowerment, autonomy, and direction.

Business leaders recognize the importance of pushing decision-making down the organization and out to the front line. Leaders must create mechanisms that keep everyone aligned to the mission and coordinated in the field. The traditional tools of management — strategy and planning — are no longer sufficient. Strategies lack guidance and plans are to rigid to adapt.

Doctrine guides decisions.

new lessons

The study of entrepreneurship is said to be abstract. That according to Zachary Yungst, co-founder cater2.me. Skills give perspective. Start-ups need good skill development to suceed.

They are:

• Sell quickly
• Build relationships
• Engage client referrals
• Understand the scope

Be aware of the market pressures - they create value.

Here's the link to the original post.

Your first set of customers will become your advisors.

world ventures

People have come together from around the world because of a new opportunity. This opportunity creates more "Fun, Freedom and Fulfillment," not only in our lives, but in the lives of others. This endeavor welcomes you.

World Ventures was envisioned as a company long before it came to fruition. The product was designed to help people.

For more information, click this link.

The Right Company at the Right Time.

relationships

Answers the needy and clingy question.

Relationship Psychology data base - Relationship Psychology

Link to the story:

http://relationshipsych.weebly.com/

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just go with it

Is today that much different than 1861-1862? In some areas, I was surprised.

Abraham Lincoln and the NSA (Just Go With It) | National Review Online

Link to the story:

http://www.nationalreview.com/corner/350787/abraham-lincoln-and-nsa-just-go-it-daniel-foster

You might be too.

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try this experiment

1) We are hard-wired to think short-term, not long-term
2) We also seem to be hard-wired to confirm to the herd mentality

We have a tendency to "anchor".

Anchoring is “our tendency to grab hold of irrelevant and often subliminal inputs in the face of uncertainty.”

Go to this zerohedge.com post and try the experiment yourself.

We usually anchor to the recent past.

the consumer culture

The definition of the consumer culture as the way enterprise apps go are social intuitive interfaces that borrow heavily from Facebook, Pinterest, Twitter, and other mainstays.

One solution is the cloud-based collaboration tool that combines social media and project management. Email for project collaboration can be difficult to manage. Plus feed images are popular with marketing team members.

Video is also becoming a popular way to communicate and share ideas.

Coordination of project teams with "spaces" for group conversations associated with calendar events and tasks are special.

When choosing a solution be sure ease-of-use is evident.

facebook phone home ~ 1776media

Facebook's Home doesn't have the features that one would expect. Is it big enough to get use to sweep others away?

http://1776media.blogspot.com/2013/06/facebook-phone-home.html?m=1


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embrace intrapreneurship

Create culture and be more productive.

Why startups should embrace intrapreneurship

Link to the story:

http://venturebeat.com/2013/06/01/why-startups-should-embrace-intrapreneurship/

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unlock new revenue

Successful design outcomes require intentional beginnings. Set clear goals, and have a partner whose skills align with your desired success. Design is a service. Design is an important strategic element of your business. Understand how it can help.

Here's some helpful, effective design tips:

• Understand your needs
• Understand your consumer
• Solve strategic problems
• Engage constantly
• Recognize and break your biases
• Understand your capacity to act
• Push beyond your comfort zone

Respect your own effort and mold a solution into something you can activate. Understand the solutions, cultural impact, and operational feasibility. If you are able to execute - do it.

will facebook go out with a bang?

Will Facebook Go Out With A Bang? – ReadWrite
Link to the story:

http://readwrite.com/2013/05/10/will-facebook-go-out-with-a-bang

So many changes and shifts in consumer web use.

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quest for the devil particle

Fermilab has been after it for quite some time.
Link to the story:

http://technorati.com/technology/article/quest-for-the-devil-particle/


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self-service hr

Passion's in there.

5 Attributes of a World-Class Workforce

Link to the story:
http://www.forbes.com/sites/meghanbiro/2013/04/14/5-attributes-of-a-world-class-workforce/

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six layers of social engagement

Time on websites went down. Time on social networks exploded. There is a new eco-system. 

The future of business: Six layers of customer engagement

Link to the businessgrow.com story:
http://www.businessesgrow.com/2013/04/14/the-future-of-business-six-layers-of-customer-engagement/

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how to use mind maps

Helps with the organization. A content helper.

HOW TO: Use Mind Maps to Write Blog Posts | mansquees from polleydan
http://polleydan.wordpress.com/2013/04/08/how-to-use-mind-maps-to-write-blog-posts/

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agatha christie: in motion

Shared from the Digg iPhone app:
The Chemistry Of The Murder Mystery

In the midst of World War I a young Englishwoman received a challenge from her sister. Could she write a mystery novel in which the true villain was impossible to guess? The response to that challenge launched one of the most successful careers in crime fiction.

http://www.wired.com/wiredscience/2013/04/the-chemistry-of-mysteries-2/?utm_source=feedburner

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the disciple

Perhaps a bridge, found in literature, between resurrection and reincarnation.

I will never look at an image of the Crucifixion in the same light again. THE DISCIPLE amazon.com/The-Disciple-e… #nonfiction #spirit #medium
— Simon Hay (@SimonHayHealer) March 31, 2013

Compelling and has my curiosity.

new book on decision making

Process has more power than analysis. Plow through the bias of decision making. 

"Decisive" is the Right Choice for Making Business and Life Decisions

Link to the story:
http://smallbiztrends.com/2013/04/decisive-decision-making-book-review.html

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what most schools don't teach

Good video why computer code should be taught in schools.
Click on the post title to watch the video.

two areas of the brain

Meeting point of the bicameral mind?

Link to the story:

Researchers have found two areas of the brain that appear to compete for control over behavior
http://psychcentral.com/blog/archives/2004/10/18/researchers-have-found-two-areas-of-the-brain-that-appear-to-compete-for-control-over-behavior/

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1776media: How to Improve Your Social Media Marketing With Bl...

1776media: How to Improve Your Social Media Marketing With Bl...: Integration of blogging content and social media. How to Improve Your Social Media Marketing With Blogging http://www.socialmediaexaminer.co...

Blogging to drive traffic.

become a lifelong learner

Education for a lifetime.

Link to the story:

How and Why to Become a Lifelong Learner
http://artofmanliness.com/2013/03/18/how-and-why-to-become-a-lifelong-learner/

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employee think

Employees are the most valuable asset. Meet during the midway point on projects.

Link to the businessinsider.com story:

Harvard Lecturer Explains How To Get Employees To Think Like Entrepreneurs
http://www.businessinsider.com/harvard-lecturer-explains-how-to-get-employees-to-think-like-entrepreneurs-2013-3

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3 keys to excel

Achieve the hat trick.

Link to the story:

3 Keys to Business Excellence
http://www.inc.com/kevin-daum/3-keys-to-business-excellence.html

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advertising: engagement and brand

Search for achievements. The evolution of mobile. 

Read the forbes.com story:

Engagement Advertising: The Future of Brand Advertising?
http://www.forbes.com/sites/gyro/2013/03/12/engagement-advertising-the-future-of-brand-advertising/

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9 entrepreneurship principles

All the work that goes on behind the scenes will pay off.

Read the smallbiztrends.com story:

9 Entrepreneurship Principles You Shouldn't Forget
http://smallbiztrends.com/2013/03/entrepreneurship-principles.html

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recognize amazing

Slow down. Awareness helps recognition.

Link to the story:

Amazing people | Aspire-CS
http://www.aspire-cs.com/amazing-people

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copywriting tips

Show a sense of urgency. However, don't come on too strong.

- StumbleUpon
http://www.stumbleupon.com/su/1faHha/digitalethos.org/copywriting-tips-to-become-an-effective-copywriter/

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list from pixar's story artist

Exercises, some to be sure and worth the effort. A good lesson in sharing. You can't share it if it's not written down.

Link to the story:

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Pixar's 22 Rules Of Storytelling

These rules were originally tweeted by Emma Coates, Pixar's Story Artist. Number 9 on the list - When you're stuck, make a list of what wouldn't happen next – is a great one and can apply to writers in all genres.

http://aerogrammestudio.com/2013/03/07/pixars-22-rules-of-storytelling/

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the killer app

Vision. Visionary. You get it.

Leadership: The Killer App That Almost Everyone Overlooks
http://www.huffingtonpost.com/landon-ray/leadership-advice_b_2832487.html

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RT @geekinfonow: What Facebook's New News Feed Means for Marketers dlvr.it/339WF2 #Advertising #Business #Facebook #Marketing
— #TechinBiz (@techinbusiness) March 7, 2013

Introducing @wildfireapp's 12 Months of Social: Non-stop social marketing tips for 2013. Check it out! bit.ly/151BJMv #12mosocial
— Wildfire by Google (@wildfireapp) February 14, 2013

Adding the most interactive tweeps and unfollowing inactives using Tweepi's geeky Twitter tools. tweepi.com/?0
— Arianna Socorro (@Arianna_Socorro) February 7, 2013

2013 online marketing trends

Consumers are researching products more.

» Online Marketing: Top Trends for 2013
http://www.adexchanger.com/data-driven-thinking/online-marketing-top-trends-for-2013/

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inferno

The release for Dan Brown's fourth book is set for May 14, 2013.
Brown said that there will be more codes, secrets, and mystery in Inferno.

talent analytics

Payroll for some companies is 40% or more of total revenue. New resources do matter.

Link to forbes.com story:

BigData in Human Resources: Talent Analytics Comes of Age
http://www.forbes.com/sites/joshbersin/2013/02/17/bigdata-in-human-resources-talent-analytics-comes-of-age/

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leaders and strategies

Solve problems and improve performance. Use employee decision making models. Leaders see to it that problems are solved. Transformational strategies motivate people through values.

Share the vision.

Link to the story from work911

LEADERS USE STRATEGIES FLEXIBLY
BALANCE LONG-TERM AND SHORT-TERM NEEDS

value motivation

Keeping Yourself Motivated - ow.ly/hulPh

— Harry Che (@GoalsOnTrack) February 18, 2013

train the brain for positivity

Affirmations deluxe. Be grateful.

Link to the story:

How to Train Your Brain to Stay Positive
http://www.entrepreneur.com/blog/225683?hootPostID=c67563815d36597f3f812ffd838d49b6

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awareness, interest, desire

The new purchase loop. 6 areas of interest.

Link to the story:

How Inbound Marketing Aligns With the New Purchase Loop
http://blog.hubspot.com/blog/tabid/6307/bid/34158/How-Inbound-Marketing-Aligns-With-the-New-Purchase-Loop.aspx

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rebranding the old

Marketing is the narrative, not the substitute. 

Link to the forbes.com story:

Lincoln and American Give Us New Branding the Old Fashioned Way: Smoke and Mirrors
http://www.forbes.com/sites/jonathansalembaskin/2013/02/09/lincoln-and-american-give-us-new-branding-the-old-fashioned-way-smoke-and-mirrors/

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what if

Tap into the creative process.

Link to forbes.com story:

The Power Of "What If"
http://www.forbes.com/sites/mikemyatt/2013/02/08/the-power-of-what-if/

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google+ content strategies

Link to story:

64 Google+ Content Strategies [Infographic]
http://www.copyblogger.com/google-plus-content-strategies/

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social media: the event

Did you miss the social event? Via the social medium?

Link to story:

How social media is becoming as important a live event as the live event itself
http://gigaom.com/2013/02/04/how-social-media-is-becoming-as-important-a-live-event-as-the-live-event-itself/

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experience vs. leadership

Where we've been to where we are going.

Link to story:

How Important is Experience to Great Leadership?
http://www.terrystarbucker.com/2013/02/03/how-important-is-experience-to-great-leadership/

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10 copywriting ideas

Artistic advertising allows you to create content marketing that effective.

copyblogger.com has a good article on 10 ways to create good copy.

Writing good copy is both an art and a science.

a new one

A self-esteem booster.

Link to story:

Guns, Boobs, and Facebook Fantasy
http://www.psychologytoday.com/blog/swim-in-denial/201301/guns-boobs-and-facebook-fantasy

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social media growth

The Growth of Social Media
Link to story:
https://gaggleamp.com/blog/the-growth-of-social-media/?utm_source=GaggleAMP-GaggleAMP&utm_medium=Twitter%20(GaggleAMP)&utm_content=13159-The%20growth%20o&utm_campaign=(GaggleAMP)&utm_source=GaggleAMP-GaggleAMP&utm_medium=Twitter%20(GaggleAMP)&utm_content=13159-The%20growth%20o&utm_campaign=(GaggleAMP)

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melding ad and the brand

Social media has revolutionized the advertising spectrum. The brand has been elevated to levels which promotes the advertising as well. The advertising platform is social media. Social media has become the brand for products that owe their success to the social media advertising platform.




Source stories: The under utilization of social media

attitude and success

If we think our best days are ahead of us, we find solutions to our problems much easier. 

Link to story:

Your Attitude Determines Whether Or Not You'll Succeed
http://www.businessinsider.com/attitude-determines-success-2013-1

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the amazing chart

It's about the economy.
Link to the story:

The Simplest Stock Market Indicator In The World Continues To Work Amazingly
http://www.businessinsider.com/january-20-sp-500-vs-initial-claims-2013-1

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self-directed play

Much can be said about the benefits of children who play on their own.

Link to story:

A More Resilient Species
http://boingboing.net/2013/01/15/a-more-resilient-species.html

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new purpose

There is a growing number of people who have started new companies that are making money. These people have a new purpose and we are part of it.

Link to story:

"Conscious Capitalism" Is Not an Oxymoron
http://blogs.hbr.org/cs/2013/01/cultivating_a_higher_conscious.html

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social interactions

People are knowledge repositories and the brain manages information. Innovation involves knowledge sharing. Social media may only offer the illusion of social connection. Value shared knowledge.

Source story for this post: Innovators are Conversational Architects

mastermind (a review)

System 1 and System 2

Link to story:

Mastermind: How To Think Like Sherlock Holmes (A Review)
http://bigthink.com/insights-of-genius/mastermind-how-to-think-like-sherlock-holmes-a-review

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alzheimer's an art

Imagination and creativity.

Link to story:

Weekend Diversion: Combatting Alzheimer's with Art
http://scienceblogs.com/startswithabang/2013/01/12/weekend-diversion-combatting-alzheimers-with-art/

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less convinced

Keeping history is all about the packaging. 

Link to story:

The more you read, the less convinced you are
http://blogs.discovermagazine.com/gnxp/2013/01/the-more-you-read-the-less-convinced-you-are/

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great literature and therapy

Reading Shakespeare and others recharge the brain. Help us reflect.

Link to story:

How reading Shakespeare and Wordsworth offer better therapy than self-help books
http://www.dailymail.co.uk/news/article-2261636/Reading-Shakespeare-provides-bigger-boost-self-help-book.html

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stories persuade people

Visuality and context are key.
Link to story:

Ten Proven Ways to Create Better Stories And Persuade People
http://www.businessinsider.com/strategies-for-persuasion-2013-1

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stories persuade people

Visuality and context are key.
Link to story:

Ten Proven Ways to Create Better Stories And Persuade People
http://www.businessinsider.com/strategies-for-persuasion-2013-1

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social media tips

New trends are dominating the social media landscape. Visualization is important. This allows us to optimize a content marketing plan. Competitive research is at a premium. This improves the social presence.

Social platforms are complementing each other. Use this to advantage. Visualization has evolved into a feature for tapping into social media resources. There was a time when social media was a striving to find a place for visualization. Not any longer.

Go mobile. Growing at a very fast pace.

Source story for this article.
6 social media trends

20 content ideas

Link to story:

20 Ideas for Content that People Love to Share on Social Media
http://www.jeffbullas.com/2013/01/10/20-ideas-for-content-that-people-love-to-share-on-social-media/

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how to change

A connection built on ideas. 
Link to story:

Failing to Start: Why We Accept Mediocrity and How to Change
http://www.socialmediaexaminer.com/failing-to-start-why-we-accept-mediocrity-and-how-to-change/

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this might not work

Taking Seth's advice, because he did.
Staying focused.
Link to story:

Seth's Blog
http://sethgodin.typepad.com/seths_blog/2013/01/out-on-a-limb.html

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new media strategy

Social media ideas according to the movie "It's a Wonderful Life". 

Link to story:

Social Media Marketing According to "It's a Wonderful Life"
http://www.forbes.com/sites/jonathansalembaskin/2013/01/05/social-media-marketing-according-to-its-a-wonderful-life/

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the powerful prosumer

You might have heard of this. A professional product with a consumer price. How about a consumer service too? Prosumers can be the guide to finding unmet demand. 1

Prosumers are a great category. They are interested in the breakthrough product and are generally able to buy the product now or in the near future.

Category creation is the ultimate growth strategy. 2
Starbucks is a prime example of a company creating categories. They did  this with espresso-based products. Consumers are receiving better products as a result.

Sources:

1. Target Profitable Prosumers
2. Category Creation Is the Ultimate Strategy

Twitter feed for source articles author: Eddie Yoon

google+

No avoiding it
Link to story:

http://online.wsj.com/article/SB10001424127887324731304578193781852024980.html

Google execs say more applications coming.

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